What Is Psoriasis - Psoriasis Definition

What Is Psoriasis - psoriasis is a non-contagious, inflammatory disease, predominantly cutaneous involvement, although on occasions it produces systemic involvement, chronic course with exacerbations.
There are several types of psoriasis. The most common is the so-called plaque psoriasis, which debuts with focal lesions, inflamed, swollen, scaly scalp, trunk, and members.

What Is Psoriasis - Psoriasis Definition

The affected regions of the skin vary depending on the type of psoriasis, although the most common areas are elbows, knees, scalp and interglutea area.
The joints are affected in 30% of cases and ocular signs appear in 10% of patients and in most of the time after the onset of the lesions on the skin. Ocular involvement is more common in men.

It produces some impact in the quality of life of patients, making it necessary to be vigilant about depressive symptoms.

What is its cause?

Its cause is unknown. You think of a multifactorial etiology. There are multiple theories: Although the cause of the loss of control on the proliferation of keratinocytes is unknown, are known causes environmental, genetic and immunological factors that play an important role in the development of the disease:

1. Environmental factors: stress is one of the best known triggers of psoriasis, as well as exacerbador agent of outbreaks, as well as the cold, obesity, trauma, infections (streptococcal, staphylococcal, HIV, etc.), alcohol, tobacco and drugs. On the contrary, climates, sunlight and pregnancy are associated with clinical improvement. The first lesion usually appears after an upper respiratory infection.
2. Genetic factors: there is a genetic predisposition for the disease. Approximately 40% of people with psoriasis or psoriatic arthritis have family history of first level.
3. Immunological factors: psoriasis could be considered an autoimmune disease, and has high levels of TNF-a in skin and blood. The increase in TNF-a levels in obese people shows association between the two entities.

That prognosis are patients diagnosed with psoriasis?

It is a benign disease, but affecting the social aspect of people. It is a disease of long evolution that courses with remissions and exacerbations and sometimes refractory to treatment.

There is a higher incidence of cardiovascular events in these patients (acute infarction myocardium, brain stroke, etc.). No association has been found between the use of biological treatments with the appearance of this type of event

One-third of patients diagnosed with psoriasis develop arthritis.

It has been concluded that they suffer a greater social limitation and a greater impact in their lives those patients presenting involvement span - planting than those that affect other areas of the body, regardless of the degree of the extension.

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