What Is Psoriasis - Psoriasis Definition

What Is Psoriasis - psoriasis is a non-contagious, inflammatory disease, predominantly cutaneous involvement, although on occasions it produces systemic involvement, chronic course with exacerbations.
There are several types of psoriasis. The most common is the so-called plaque psoriasis, which debuts with focal lesions, inflamed, swollen, scaly scalp, trunk, and members.

What Is Psoriasis - Psoriasis Definition

The affected regions of the skin vary depending on the type of psoriasis, although the most common areas are elbows, knees, scalp and interglutea area.
The joints are affected in 30% of cases and ocular signs appear in 10% of patients and in most of the time after the onset of the lesions on the skin. Ocular involvement is more common in men.

It produces some impact in the quality of life of patients, making it necessary to be vigilant about depressive symptoms.

What is its cause?

Its cause is unknown. You think of a multifactorial etiology. There are multiple theories: Although the cause of the loss of control on the proliferation of keratinocytes is unknown, are known causes environmental, genetic and immunological factors that play an important role in the development of the disease:

1. Environmental factors: stress is one of the best known triggers of psoriasis, as well as exacerbador agent of outbreaks, as well as the cold, obesity, trauma, infections (streptococcal, staphylococcal, HIV, etc.), alcohol, tobacco and drugs. On the contrary, climates, sunlight and pregnancy are associated with clinical improvement. The first lesion usually appears after an upper respiratory infection.
2. Genetic factors: there is a genetic predisposition for the disease. Approximately 40% of people with psoriasis or psoriatic arthritis have family history of first level.
3. Immunological factors: psoriasis could be considered an autoimmune disease, and has high levels of TNF-a in skin and blood. The increase in TNF-a levels in obese people shows association between the two entities.

That prognosis are patients diagnosed with psoriasis?

It is a benign disease, but affecting the social aspect of people. It is a disease of long evolution that courses with remissions and exacerbations and sometimes refractory to treatment.

There is a higher incidence of cardiovascular events in these patients (acute infarction myocardium, brain stroke, etc.). No association has been found between the use of biological treatments with the appearance of this type of event

One-third of patients diagnosed with psoriasis develop arthritis.

It has been concluded that they suffer a greater social limitation and a greater impact in their lives those patients presenting involvement span - planting than those that affect other areas of the body, regardless of the degree of the extension.

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Scalp Psoriasis - Psoriasis Scalp

Scalp Psoriasis - Psoriasis of the scalp is the same disease that affects any part of the body, in this cells reproduce very quickly and produce scaling on the surface of the skin, which when it accumulates adopts the characteristic of psoriasis silvery or whitish appearance.

Scalp Psoriasis

Psoriasis of the scalp, both the Elimination of the scales and the application of treatment are complicated by the presence of the hair, the treatment involves initially remove the scales and then apply treatment to reduce psoriasis lesions.

Scalp Psoriasis - Psoriasis Scalp

Initially, to remove the scales it is necessary to apply oil or Vaseline to moisten the flakes, when they are softened, the washed often, or with the help of a comb is easy to remove the scales, once got this treatment must be applied directly to the scalp.

Some of the substances used to remove the scales can be best applied after a bath or hot shower, but this varies from patient to patient. The products generally used to remove the scales include Urea, salicylic acid, benzoyl peroxide, and derived from coal tar. These products should be used without being directly applied on the hair, have to be applied on the scalp. Once applied the product and after a variable period of treatment is easy to blow up the scales with a soft hairstyle. Try to start strongly adherent scales can be detrimental for psoriasis, since vigorous scratching can be output more psoriasis or could cause infections. Try to start the scales that have not been softened with the treatment also can cause the breaking of hair that is present in the area of the scales, that hair will grow again, but it may require some time.

You can use a cleansing shampoo and subsequently when the scales are removed a tar shampoo should be used. Tar shampoos are a good treatment of psoriasis should be used and then the hair should rinse thoroughly. Treatment shampoos generally dry hair so the further use of air conditioners and hair softener is advisable. If the treatment causes redness, itching or discomfort, they can use is corticosteroid spray or these same products into account drops. The use of antihistamines products is advisable in certain patients.

The frequency of application of treatments depends on the severity of the psoriasis, when it is in an important outbreak treatment should be applied frequently and to measure that improves must go spacing treatment.

Because of the barrier posed by the hair, the use of ultraviolet light in the treatment of psoriasis of the scalp is very limited, they have recently come to market about combs with built-in ultraviolet light, this treatment can be used in some cases under medical prescription.

Once solved the outbreak of psoriasis, the frequent use of tar shampoos, twice a week, leaving the shampoo on the scalp 5 minutes, this will allow you to reduce outbreaks of psoriasis of the scalp. If you want you can use tar shampoo daily.

Questions that we frequently raise patients with psoriasis of the scalp.

It produces the psoriasis hair loss? What can be done to prevent hair from falling? : Psoriasis can cause hair loss, but this fall is temporary since the hair will grow again, the reason for the fall is due to the inflammation that accompanies psoriasis, so an adequate treatment of psoriasis to stop the hair loss.

Tar products spoil much hair what can be done to prevent it? : Almost all treatments for scalp psoriasis are little acceptable cosmetically, the most advisable is to apply the treatment at night and by morning proceed to wash the scalp, if the spray or shampoo produce you dryness of hair it is advisable to use oil or conditioners

Do you use dyes, fasteners, spray or permanent hair if I have psoriasis? : Some patients refer to not tolerate the application of these products other patients referred to use them without problems, it is best not to use very strong products and preferably without alcohol.

Is a the haircut necessary if I have psoriasis? : Take a short hair, the use of permanent are general techniques preferred by patients with psoriasis by the ease of application of treatments, but actually cutting hair does not influence at all the evolution of psoriasis. The use of air dryers helps remove the scales of the hair.

What are the best ways to blow up the scales? : Many substances there are lubricants that help blow up the scales, the simplest are the use of oils of child, olive oil, oil of snowy, tar oils and conditioners for the hair. These products are applied in Flake overnight and left in contact with Flake overnight or for several hours, it is more effective if it covered the head with a plastic cap or towel. In the morning, and with the help of a soft comb is easy to jump the scales and then wash the head with a tar shampoo

Are they effective tar shampoos? : The effectiveness varies from one patient to another. Several studies have shown that with tar shampoos are superior to others in the treatment of psoriasis. These shampoos are left in contact with the scalp between 5 and 10 minutes, since in this way I could penetrate into the flake. Once used during this time the hair must be clarified and if you want to you can use another shampoo that cosmetically you like better.

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Pustular Psoriasis - Palmoplantar Pustular Psoriasis

Pustular Psoriasis - It is more frequent in the fifth or sixth decade of life, has a female predominance, with a woman relationship: 3:1 man. The exact cause and pathogenesis of the disease remains unknown, and there is debate about whether the PPP is a variant of psoriasis or a different condition. Although 18% of patients have lesions of psoriasis in any part of the body, the genetic characteristics of PPP are different from the vulgar psoriasis. Reported associations with thyroid disease, celiac disease / gluten intolerance, consumption of tobacco and type 2 diabetes. The condition worsens by allergies to metals, psychosocial stress, focal infection like tonsillitis.

Pustular Psoriasis - Palmoplantar Pustular Psoriasis

More recently, case reports point to a potentially paradoxical reaction to the tumor necrosis factor inhibition alfa-terapia, which can worsen an existing PPP or trigger a new beginning of PPP. A review of the literature reveals that various types of treatments have been used in PPP over the years, ranging from topical corticosteroids, Anthralin, phototherapy, Grenz Ray, retinoids, tetracyclines and Cyclosporine to biologic therapies. The lack of well documented clinical studies makes it difficult to select an ideal treatment, and the literature on PPP is restricted to case reports or small case series. The purpose of this review is to discuss the current treatment for PPP therapies, based on the results of randomized clinical trials.

Treatments

Topical corticosteroids and topical retinoids
Topical agents remain the treatment more used in the treatment of PPP, even when the disease is usually tough, and topical steroids are the most commonly prescribed medications in PPP. Corticosteroids prevent the formation of new pustules, especially when applied under occlusion, but prolonged use of corticosteroids is not advisable due to adverse effects well-known and disadvantages. Referrals by the topical corticosteroids are temporary.
Topical retinoids can be used to prevent adverse effects or reinforce the effects of steroids, but there were no controlled studies of the effectiveness of topical retinoids in PPP. Tazarotene is the preferred drug.

Systemic retinoids

Studies investigating the effectiveness of oral retinoids in PPP, most evaluate the efficacy of etretinate. Oral etretinate 0.6 - 1 mg/kg/day produced improvement in nearly two thirds of patients with PPP, in a study Lassus and Geiger reported that the acitretin is as effective as etretinate in the treatment of PPP, and may be used at the same dose. Meta-analysis have shown improvement complete or excellent in 39% of cases after 12 weeks of treatment with oral retinoids, and acitretin not only decreased the number of pustules, but it also helped control of coexisting hyperkeratosis. During treatment with acitretin, is required dose according to the weight adjustment. The drug can be administered alone or in combination with psoralen more UVA (PUVA) where also required a dose adjustment.

Phototherapy

PUVA, with oral or topical psoralen in the treatment of PPP has been used. Murray and cabbage and Rosen and col reported that oral local PUVA is more effective than placebo and 176-228 J/cm2 UVA dose is required to control the disease, however, were lower percentages of responses by others. The main advantage of topical PUVA on oral PUVA is to avoid the potential adverse effects of systemic therapy, so it is preferred the topical PUVA for selected patients with gastrointestinal or liver disease or patients with cataracts.
Many studies failed to show the effectiveness of topical PUVA in PPP. It showed that oral PUVA, etretinate and PUVA, topical or oral or combinations were superior to topical PUVA only with regard to effectiveness and efficiency in PPP home.
It has investigated the value of PUVA in maintenance therapy. Nielsen and Madsen reported that 3 of 9 patients with PPP receiving PUVA for short time then of the remissions achieved Corticoid under occlusion not relapsed in the coming year. Ettler and Richards reported that 2 weeks relapses occurred in 10 patients after completed acitretin, despite therapy PUVA therapy, so topical PUVA was only unable to maintain remission after therapy with acitretin.
These findings call into question the role of PUVA as maintenance therapy.

Cyclosporine

Many studies have investigated the effectiveness of Cyclosporine in patients with PPP. Low-dose Cyclosporine (1 - 2.5 mg/kg/day) is an effective treatment of choice in 2/3 of patients with PPP. Erkko and col evaluated the dose of Cyclosporine that is sufficient to control the activity of the disease in a study that included 58 patients with PPP, and found that 1 - 2 mg/kg/day of Cyclosporine was effective in the majority of patients. The study began with a dose of 1 - 2 mg/kg/day of Cyclosporine for 4-8 weeks and 4 mg/kg/day dose increased only in patients who did not have a satisfactory response with the lowest dose. In the follow-up period, there was an increase of pustules to 12 months after the suspension of the treatment, but average values not exceeded baseline values at each stage.
The use of low-dose Cyclosporine may prevent the dose-related toxicity (e.g. hypertension, Nephrotoxicity) Cyclosporine, and achieve a greater acceptance of Cyclosporine in the treatment of PPP. The development of Generalised Pustular psoriasis then discontinue Cyclosporine is a cause for concern. Although it is a complication rarely reported, gradual decrease in Cyclosporine strategies are developed to avoid it.
Colchicine
The efficacy of colchicine on PPP has been shown for 30 years. Thestrup-Pedersen and Reymann reported significant improvement with colchicine in 10 of 27 cases, and Takigawa et al. found it effective in 13 of 32 cases in 2-8 weeks of treatment in a non-controlled trial. However, controlled studies not randomised trials did not support this efficiency.
Other treatments
There is only limited experience of radiotherapy Grenz and tetracyclines in PPP. Controlled trials there are not current trials that show some effectiveness of methotrexate, Anthralin or topical retinoids for the treatment of PPP.
The evidence in the treatment of PPP is inadequate and unsatisfactory. So it is needed further investigation to discover better treatments and validate the current therapeutic options.
What does this article to the Dermatologic practice?
Pustulosis palmoplantar (PPP) is a pustular dermatosis chronic and recurrent characterized by multiple sterile pustules and plates erythematous on palms and soles.
The exact cause of the pathogenesis of the disease remains unknown and there is still a debate on whether it is a variant of psoriasis or a different condition. Several treatments exist for this disease. The purpose of this review is to discuss the treatment options for PPP, based on randomized controlled trials.

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Psoriasis Treatment - Scalp Psoriasis Treatment

Psoriasis Treatment - Psoriasis is a skin disease that generally causes itching or painful patches of thickened skin reddened with greyish scales. Psoriasis is frequent to appear on shoulders, knees, scalp, back, face, palms of hands and soles of the feet, although it can also occur in other locations.

The main cause of psoriasis seems to be associated with an alteration of the immune system. Under normal conditions, in the process of cell replacement, the new skin cells that grow in the deepest part of the same, rise to the surface in a process that usually takes about a month. However, in the patients suffering from psoriasis, this process occurs quickly and takes place in a few days since the new cells are moving too fast. The symptoms mentioned symptoms come and go with a high interpersonal variability, and all indications are that there are various elements that can modify the prognosis. Among the most obvious are: infections, stress, have dry skin and certain drugs. In addition, and without being hereditary, there is a certain genetic predisposition.

Specific dietary treatment? Not

The Dietitians-nutritionists don't tackle cases of psoriasis. The reason is clear, neither in the pathogenesis of the disease and possible treatments there is no priori dietary elements that seem to be related. In the opposite direction, some alternative therapists, not infrequently (alternative) health therapists resort to strange dietary formulations with the patients suffering from this disease.

Psoriasis Treatment - Scalp Psoriasis Treatment

As is often the case with many other chronic enefermedades, difficult to solve or mechanisms not yet very well enlightened etiopatologicos, "alternative" proposals appear to be a valid solution for some often desperate patients. And is is not for less, psoriasis, as well as the uncomfortable of their symptoms can affect significantly sufferers to involve an erosion of its image and, therefore, affect their social relations. I.e. it's a disease that impacts highlighted the physical well-being, both in the psychological and social of the patients.

For these reasons, it is not uncommon to finish by resorting to certain therapists framed within the alternative and complementary medicine. Among this type of treatment are frequent balneotherapy, acupuncture, chiropractic, homeopathy, aromatherapy, or "floral" treatments. And of course, the proposal of the most varied diets in combination with dietary supplements. However, the National Psoriasis Foundation of United States States that the result of this kind of "alternative" interventions is both or more variable between different individuals than 'conventional' treatments. Put another way, that what has worked one does not have work for you to another. Assuming, this what I say, that improvement can be attributed you reliably mentioned treatment or placebo effect.

In fact the theme of today comes as a result of a query that I made the other day a reader that a Naturopath doctor recommended a diet relatively normal but strict at the same time with the inclusion of some elements that could not be jump under any circumstances: the breakfast would be strictly 3 pears, 2 blocks and a few hazelnuts; the use of omega three supplements; a hepatic debugger (do not know what specifically) etc.

In all honesty I have no arguments to say that this pattern will go right or wrong for the improvement of their psoriasis, but at the same time it, the doctor naturopath, do not think having them to say that Yes it will go well. Therefore that show is so clear-cut as to what we are going to go right (or wrong) does not seem a good attendance.

To finish and to summarize, conclude that today there is no any serious dietary guideline that has been standardized, nor any indication of supplementation, for patients with psoriasis whatever its type. In the opposite direction the recommendations of all the associations involved in this issue in general, recommend a balanced diet, avoid toxic habits (alcohol and tobacco) and exercise. In all cases of chronic diseases, including psoriasis, patients should be wary of claims or slogans of the type "healing treatments", since these do not exist and, in a good part of the cases, it is fraud that play and take advantage of the good faith, the lack of medical knowledge and the desperation of some affected.

I.e. our food does not have a direct influence on the evolution of the psoriasis, but a proper lifestyle can help to keep the skin in a better State.

Before dismissing me, and as it is becoming usual in this blog when this type of topics are addressed, would recommend to those interested persons or their families to contact with any association of recognized solvency. In our environment action Psoriasis is one of them, just in case the main on the national scene, an association that has a web page of interesting content.

You can read another articles like Psoriasis Causes,  Psoriasis Symptoms, and Psoriasis Tips.



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Psoriasis Tips - Tips for psoriasis

Psoriasis Tips - People suffering from psoriasis must always follow custom recommendations that your dermatologist will give you to prevent outbreaks or a worsening of the disease. However, there are some general tips that can help keep the psoriasis.

Tips for psoriasis

1. it is important to keep the skin well hydrated. Drying, as well as produce itching and irritations, can make psoriasis worse. You must opt for very mild soaps or cleaning lotions containing no SOAP. The use of abrasive soaps and sponges or mittens that by its composition or texture can have an irritating effect must be ruled out. It is also highly recommended to take baths for relaxing and antiescamativo effect. If added to water action emollient oils its beneficial effects will be strengthened even more. The same is true of balneotherapy, that the application of mud, salts, sulphurous waters and moisturizing treatments have very healthy results, both for the skin and for the well-being of the patient.

Psoriasis Tips - Tips for psoriasis

2. the physical injuries trigger lesions or produce new. You should avoid, as far as possible, the wounds, the continued friction, hits, scrapes, injuries or solar or accidental burns. Any of these attacks can lead to a re-emergence of the disease within one or two weeks.


3. Beware of the weight. It has been shown that there is a relationship between excess weight and psoriasis.


4. certain medications may aggravate it or trigger it. Very common drugs can induce, aggravate or trigger psoriasis, so it is important that the disease is well diagnosed by a specialist and that it monitor the medications that may be incompatible.


5 the treatment must be adapted to certain situations. In women, psoriasis outbreaks are more common when there are periods of hormonal activity special, such as adolescents, postpartum or menopause, among others.


6 avoid temperature conditions extreme, cement dust and excessive alcohol.


7. eye with certain acute infectious processes. Colds, flu and tonsils can cause or trigger an outbreak of psoriasis. They should be treated early and properly.

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Psoriasis Symptoms - Symptoms Of Psoriasis

Psoriasis Symptoms - Psoriasis is a chronic disease in the skin that affects the process of cell renewal. In fact, this disease speeds the process and makes new cells to accumulate on the surface of the skin. This fact can trigger pain, swelling and discoloration.

The real cause of this disease is not yet fully clear. However, we have identified some factors that could generate it. These are:

1. Infections
2. Injuries on the skin, the result of a rash, a sting or sunstroke
3. Stress
4. Smoking
5. Excessive consumption of alcohol

Psoriasis Symptoms - Symptoms Of Psoriasis

What are the symptoms of psoriasis?

Psoriasis usually affect the scalp, back, elbows and buttocks. Their symptoms vary from one person to another. The most common are:

• Red plaques covered with small scales
• Cracked, dry skin, bleeding
• Burning and pain
• Coarse and damaged nails
• Swollen or stiff joints
• If you suffer from any of these symptoms, see your doctor immediately. He will prescribe you the most proper medication to treat this disease. You don't have to be.

If you want to learn more about the symptoms of other diseases, see internal hemorrhoids symptoms
or symptoms of endometriosis.

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Psoriasis On Glans

Psoriasis On Glans - In case of known whitish plaques on the Glans or red lesions and dry, you should go to the doctor without waiting for the regress problem by itself, because it could be psoriasis.

Psoriasis On Glans

Psoriasis on the Glans is a chronic, inflammatory origin, which affects the final part of the conical shape. With the care you can regress the demonstrations, but the same tend to reappear over time so it's good to check in often so you have minor effects. It is good to clarify from the outset that this is not an infectious disease that can be transmitted and then from that point of view you can feel comfortable.

Psoriasis On Glans

Psoriasis is characterized by an increase in the production of skin cells that did not arrive in ripening and thus form the plaques. When it hits the Glans, the lesions take on the appearance of Red plaques with defined edges, in some cases also manifests a Halo with appearance of erythema. These characteristics, which differentiate psoriasis on the Glans from other types, the rarity of this form sometimes make it difficult to diagnose.

Among the possible solutions of psoriasis on the Glans that will be proposed, there is the circumcision, the surgical removal with the skin covering the penis to the glans. Circumcision can be considered a permanent solution to the Psoriasis on the Glans because deleting there is skin cell production. If you don't want to undergo this surgery or postpone it can treat psoriatic through manifestations of corticosteroid drugs for topical use. In this area usually is also prescribed the use of preparations for refreshing and absorbing action based on zinc oxide and the use of dead sea salt for washing, they are able to reduce inflammation. To remove the plates you can use emollients and treatments is also recommended cleansing with olive oil.

It is likely to be prescribed the use of supplements of vitamin D, which regulates the differentiation of keratinocytes. This important vitamin is produced by the human body based on the exposure to the Sun. Psoriasis is usually also recommended the use of UV lamps, but in the case of psoriasis on the Glans better avoid exposure to UV rays for the delicacy of this area.
Less frequent is the prescription medication to combat systemic psoriasis on the glans.

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